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[Ad hoc announcement pursuant to Art. 53 LR] Roche announces positive Phase II results for dual GLP-1/GIP receptor agonist enicepatide in people living with type 2 diabetes and overweight or obesity

Basel, 22 September 2026 – Roche (SIX: RO, ROP; OTCQX: RHHBY) today announced positive topline results from CT-388-104, a Phase II clinical trial evaluating enicepatide (CT-388), an investigational, once-weekly dual GLP-1/GIP receptor agonist, in adults living with type 2 diabetes (T2D) and overweight or obesity. In the study, enicepatide met both primary endpoints, delivering dose-dependent and clinically meaningful reductions in blood glucose and body weight at 48 weeks. Patients receiving the highest titrated dose (24 mg) achieved an HbA1c reduction of 2.65% (from a baseline HbA1c of 8.1%). Furthermore, 90% of patients in the 24 mg cohort reached an HbA1c level of ≤6.5% (diagnostic threshold for T2D) and 62% achieved normoglycemia (HbA1c < 5.7%), restoring blood glucose levels to a non-diabetic range. The mean weight loss at 48 weeks in the 24 mg enicepatide arm was 15.5% without a demonstrable plateau.

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match.asia Builds AI-Native Investment Bank for Southeast Asian SMEs

AI-native M&A model combines experienced deal professionals and technology to provide selected SMEs with success-fee-only transaction facilitation, broader buyer access and stronger execution support 

AI-native M&A model combines experienced deal professionals and technology to provide selected SMEs with success-fee-only transaction facilitation, broader buyer access and stronger execution support

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Leader’s Advantage Acquisition Corp. Announces Closing of $150,000,000 Initial Public Offering

Mt laurel Township, NJ, Sept. 21, 2026 (GLOBE NEWSWIRE) — Leader’s Advantage Acquisition Corp. (Nasdaq: LEDRU) (the “Company”), a blank check company whose business purpose is to effect a merger, amalgamation, share exchange, asset acquisition, share purchase, reorganization or similar business combination with one or more businesses, announced today the closing of its previously announced initial public offering of 15,000,000 units. The units were sold at a price of $10.00 per unit. The Company’s units began trading on September 18, 2026 on the Nasdaq Global Market under the symbol “LEDRU”. Each unit consists of one Class A ordinary share and one-half of one redeemable warrant. Each whole warrant is exercisable to purchase one Class A ordinary share of the Company at a price of $11.50 per share. Only whole warrants are exercisable and will trade. Once the securities comprising the units begin separate trading, the Class A ordinary shares and warrants are expected to be listed on the Nasdaq Global Market under the ticker symbols “LEDR” and “LEDRW,” respectively.

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MARKSMEN ANNOUNCES CLOSING OF PRIVATE PLACEMENT

CALGARY, ALBERTA, Sept. 21, 2026 (GLOBE NEWSWIRE) — Marksmen Energy Inc. (“Marksmen” or the “Company“) announces that it has completed the closing of its previously announced non-brokered private placement of common shares (the “Common Shares“) of Marksmen (the “Offering“). The Company issued 4,324,291 Common Shares at a price of $0.12 per Common Share for aggregate gross proceeds of $518,915.

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Crypto News Today: Pepeto Announces 162% APY Staking While Solana Price Prediction Points to $702

Dubai, UAE, Sept. 21, 2026 (GLOBE NEWSWIRE) —

Pepeto has announced its staking program now pays 162% APY, one of the strongest passive earning rates in crypto, while the presale keeps climbing past $11 million in a downturn that stopped almost everything else. That pace makes this the biggest story in crypto news today for anyone looking for an early entry, and it raises one question: what do these buyers see? Smart money answers that question the same way every time, by comparing every option on the table. 

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Fluoropolymer Coatings Market Advances as High-Performance Surface Protection Gains Ground Across Demanding Industrial Applications

As per SNS Insider, the Fluoropolymer Coatings Market is projected to reach USD 4.80 Billion by 2035, growing at a 5.28% CAGR, while the U.S. market is expected to reach USD 2.12 billion, advancing at 5.82% CAGR, as demand rises for durable, corrosion-resistant surface protection. 

As per SNS Insider, the Fluoropolymer Coatings Market is projected to reach USD 4.80 Billion by 2035, growing at a 5.28% CAGR, while the U.S. market is expected to reach USD 2.12 billion, advancing at 5.82% CAGR, as demand rises for durable, corrosion-resistant surface protection.

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Host Digital Inc. Announces Closing of Common Stock Offering

NEW YORK, NY, Sept. 21, 2026 (GLOBE NEWSWIRE) — Host Digital Inc. (f/k/a Healthy Choice Wellness Corp.) (NYSE American: HOST) (the “Company” or “Host Digital”) today announced the closing of its previously announced underwritten public offering (the “Offering”) of 2,187,500 shares of its Class A common stock, par value $0.001 (the “Common Stock”), at a public offering price of $8.00 per share.

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LI BANG INTERNATIONAL CORPORATION INC. Announces Adjournment of Extraordinary General Meeting

JIANGYIN, China, Sept. 21, 2026 (GLOBE NEWSWIRE) — Li Bang International Corporation Inc. (“Li Bang International”) and its subsidiaries (collectively, the “Company,” “we,” “us,” “our company,” or “Li Bang”) (Nasdaq: LBGJ), a company engaged in designing, developing, producing, and selling stainless steel commercial kitchen equipment in China, today announced that its Extraordinary General Meeting of Shareholders (the “Meeting”) has been adjourned to September 22, 2026 at 9:30 a.m., Eastern Time, at the Company’s principal office, due to the absence of a quorum.

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